WELSH - Floyd and Nancy Istre have been married for nearly seven years and oversee a busy household that includes Mark, 7, Isaac, 5, and Amelia, who will celebrate her first birthday in August.
If you mention Ann Marie to the brothers, they know you are talking about the thirdborn in their family, the sister who arrived 14 months before Amelia. The world itself might one day know Ann Marie as someone who saved millions of lives.
A diagnosis and a decision